ID   4.2.3.98
DE   (+)-T-muurolol synthase.
CA   (2E,6E)-farnesyl diphosphate + H2O = (+)-T-muurolol + diphosphate.
CC   -!- The cyclization mechanism involves an intermediate nerolidyl
CC       diphosphate leading to a helminthogermacradienyl cation.
CC   -!- After a 1,3-hydride shift of the original 1-pro-S hydrogen of
CC       farnesyl diphosphate, cyclization and deprotonation result in (+)-T-
CC       muurolol.
DR   A7NH01, TMUUS_ROSCS;  B5GW45, TMUUS_STRCL;
//