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ENZYME entry: EC 4.2.99.24

Accepted Name
Thebaine synthase.
Alternative Name(s)
THS.
Reaction catalysed
(7S)-salutaridinol 7-O-acetate <=> thebaine + acetate
Comment(s)
  • Isolated from the plant Papaver somniferum (opium poppy).
  • The reaction occurs spontaneously when the pH is between 8-9, but the enzyme is required at the physiological pH, which is close to 7.
Cross-references
BRENDA4.2.99.24
EC2PDB4.2.99.24
ExplorEnz4.2.99.24
PRIAM enzyme-specific profiles4.2.99.24
KEGG Ligand Database for Enzyme Nomenclature4.2.99.24
IUBMB Enzyme Nomenclature4.2.99.24
IntEnz4.2.99.24
MEDLINEFind literature relating to 4.2.99.24
MetaCyc4.2.99.24
Rhea expert-curated reactions4.2.99.24
UniProtKB/Swiss-Prot
A0A2U9GHG9, THS1_PAPSO;  A0A2U9GGW3, THS2_PAPSO;  

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