ID   4.3.1.32
DE   7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase.
AN   F0-synthase.
AN   FO synthase.
CA   5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil +
CA   S-adenosyl-L-methionine = 5'-deoxyadenosine + 7,8-didemethyl-8-hydroxy-5-
CA   deazariboflavin + H(+) + L-methionine + NH4(+).
CC   -!- The enzyme produces the 7,8-didemethyl-8-hydroxy-5-deazariboflavin
CC       (F0) precursor of factor 420 (coenzyme F420), a metabolite found in
CC       methanogens and in various actinobacteria.
CC   -!- F0 is also produced by some cyanobacteria and eukaryotes.
CC   -!- The enzyme, which forms a complex with EC 2.5.1.147, is a radical SAM
CC       enzyme that uses the 5'-deoxyadenosyl radical to catalyze the
CC       condensation reaction.
CC   -!- Formerly EC 2.5.1.77.
DR   O29461, COFG_ARCFU ;  Q7NIT2, COFG_GLOVI ;  Q5UXN0, COFG_HALMA ;
DR   B0R6P8, COFG_HALS3 ;  Q9HNU9, COFG_HALSA ;  A6UVH0, COFG_META3 ;
DR   Q8TQP9, COFG_METAC ;  A7IAF4, COFG_METB6 ;  Q466A4, COFG_METBF ;
DR   Q12WF6, COFG_METBU ;  Q57888, COFG_METJA ;  Q8TWY3, COFG_METKA ;
DR   A4FXR1, COFG_METM5 ;  A9AB67, COFG_METM6 ;  A6VFG8, COFG_METM7 ;
DR   Q8PU55, COFG_METMA ;  A3CWL4, COFG_METMJ ;  Q6LYV9, COFG_METMP ;
DR   B8GGS3, COFG_METPE ;  A5UM12, COFG_METS3 ;  O27266, COFG_METTH ;
DR   A0B5P5, COFG_METTP ;  A6UN87, COFG_METVS ;  Q8YR77, COFG_NOSS1 ;
DR   Q31PU7, COFG_SYNE7 ;  Q5N4D1, COFG_SYNP6 ;  P73191, COFG_SYNY3 ;
DR   Q8DIR6, COFG_THEVB ;  Q11A09, COFG_TRIEI ;  Q3MCR5, COFG_TRIV2 ;
DR   Q7U0G9, FBIC_MYCBO ;  Q9CBX6, FBIC_MYCLE ;  Q73WP9, FBIC_MYCPA ;
DR   P9WP76, FBIC_MYCTO ;  P9WP77, FBIC_MYCTU ;  Q5YQD7, FBIC_NOCFA ;
DR   Q82GV2, FBIC_STRAW ;  Q9KZZ7, FBIC_STRCO ;
//