ID 4.3.2.8 DE gamma-glutamylamine cyclotransferase. CA epsilon-(gamma-L-glutamyl)-L-lysine = 5-oxo-L-proline + L-lysine. CC -!- The enzyme, found in vertebrates, has no activity toward alpha- CC (gamma-L-glutamyl)-L-amino acids (cf. EC 4.3.2.9). CC -!- The enzyme acts as a cyclotransferase, cleaving the amide bond via CC transamidation using the alpha-amine of the gamma-L-glutamyl residue, CC releasing it as the cyclic 5-oxo-L-proline. DR A0JMM9, GGACA_DANRE; Q66I06, GGACB_DANRE; A3KNL6, GGACC_DANRE; DR Q0VFX9, GGACT_BOVIN; Q9BVM4, GGACT_HUMAN; Q923B0, GGACT_MOUSE; DR Q4KM86, GGACT_RAT ; Q66KX0, GGACT_XENLA; //