ID 4.3.99.3 DE 7-carboxy-7-deazaguanine synthase. AN 7-carboxy-7-carbaguanine synthase. CA 6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + CA NH4(+). CC -!- The enzyme is a member of the superfamily of S-adenosyl-L-methionine- CC dependent radical (radical AdoMet) enzymes. CC -!- Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an CC exchangeable S-adenosyl-L-methionine molecule. CC -!- The S-adenosyl-L-methionine is catalytic as it is regenerated at the CC end of the reaction. CC -!- The reaction is part of the biosynthesis pathway of queuosine. DR A9CF16, QUEE_AGRFC ; O67826, QUEE_AQUAE ; O29808, QUEE_ARCFU ; DR Q81G67, QUEE_BACCR ; O31677, QUEE_BACSU ; Q89ZC3, QUEE_BACTN ; DR Q7VVJ8, QUEE_BORPE ; Q89SC0, QUEE_BRADU ; Q8K9D9, QUEE_BUCAP ; DR A0A0H3KB22, QUEE_BURM1 ; Q0PBX7, QUEE_CAMJE ; Q9A3P3, QUEE_CAUVC ; DR Q8KFK8, QUEE_CHLTE ; Q97D55, QUEE_CLOAB ; Q728E5, QUEE_DESVH ; DR P64555, QUEE_ECO57 ; P64554, QUEE_ECOLI ; A6H1N2, QUEE_FLAPJ ; DR Q74CF3, QUEE_GEOSL ; Q7NCE3, QUEE_GLOVI ; P45097, QUEE_HAEIN ; DR B0R9W6, QUEE_HALS3 ; A2BJ90, QUEE_HYPBU ; Q1IHK7, QUEE_KORVE ; DR Q8EZ24, QUEE_LEPIN ; Q8TIF5, QUEE_METAC ; Q2FS67, QUEE_METHJ ; DR Q59039, QUEE_METJA ; Q8TX58, QUEE_METKA ; O27295, QUEE_METTH ; DR Q9K0Q5, QUEE_NEIMB ; Q7V9H9, QUEE_PROMA ; Q8ZZZ0, QUEE_PYRAE ; DR Q7UVG8, QUEE_RHOBA ; Q2RSY6, QUEE_RHORT ; Q9ZCV2, QUEE_RICPR ; DR P64556, QUEE_SHIFL ; P73667, QUEE_SYNY3 ; Q9HII0, QUEE_THEAC ; DR Q5JGE6, QUEE_THEKO ; //