ID   4.4.1.2
DE   homocysteine desulfhydrase.
AN   homocysteine desulfurase.
CA   L-homocysteine + H2O = 2-oxobutanoate + hydrogen sulfide + NH4(+) + H(+).
CC   -!- The enzyme cleaves a carbon-sulfur bond, releasing hydrogen sulfide
CC       and an unstable enamine product that tautomerizes to an imine form,
CC       which undergoes a hydrolytic deamination to form 2-oxobutanoate and
CC       ammonia.
CC   -!- The latter reaction, which can occur spontaneously, can also be
CC       catalyzed by EC 3.5.99.10.
DR   Q55DV9, CGL_DICDI  ;  P32929, CGL_HUMAN  ;  Q60HG7, CGL_MACFA  ;
DR   Q8VCN5, CGL_MOUSE  ;  Q19QT7, CGL_PIG    ;  P18757, CGL_RAT    ;
DR   O05394, MCCB_BACSU ;  A0A2H1K3G9, MEGL_BREAU ;  A0A1H1YBL2, MEGL_BRESA ;
DR   Q8RDT4, MEGL_FUSNN ;  Q8L0X4, MEGL_FUSNP ;  Q7MX71, MEGL_PORGI ;
DR   P13254, MEGL_PSEPU ;  Q826W3, MEGL_STRAW ;  Q73KL7, MEGL_TREDE ;
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