ID 4.5.1.2 DE 3-chloro-D-alanine dehydrochlorinase. CA 3-chloro-D-alanine + H2O = chloride + H(+) + NH4(+) + pyruvate. CC -!- The enzyme cleaves a carbon-chlorine bond, releasing a chloride and CC an unstable enamine product that tautomerizes to an imine form, which CC undergoes a hydrolytic deamination to form pyruvate and ammonia. CC -!- The latter reaction, which can occur spontaneously, can also be CC catalyzed by EC 3.5.99.10. CC -!- The enzyme's activity can also result in beta-replacement reactions, CC e.g. in the presence of hydrogen sulfide it can convert 3-chloro-D- CC alanine into D-cysteine and chloride. //