ID   4.6.1.19
DE   ribonuclease T2.
AN   ribonuclease II.
CA   a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-
CA   ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+).
CC   -!- A widely distributed family of related enzymes found in protozoans,
CC       plants, bacteria, animals and viruses that cleave ssRNA 3'-phosphate
CC       group with little base specificity.
CC   -!- The enzyme catalyzes a two-stage endonucleolytic cleavage.
CC   -!- The first reaction produces 5'-hydroxy-phosphooligonucletides and
CC       3'-phosphooligonucleotides ending with a 2',3'-cyclic phosphodiester,
CC       which are released from the enzyme.
CC   -!- The enzyme then hydrolyzes the cyclic products in a second reaction
CC       that takes place only when all the susceptible 3',5'-phosphodiester
CC       bonds have been cyclised.
CC   -!- The second reaction is a reversal of the first reaction using the
CC       hydroxyl group of water instead of the 5'-hydroxyl group of ribose.
CC   -!- The overall process is that of a phosphorus-oxygen lyase followed by
CC       hydrolysis to form the 3'-nucleotides.
CC   -!- Formerly EC 2.7.7.17, EC 3.1.4.23 and EC 3.1.27.1.
DR   Q96662, POLG_BVDVC ;  P19711, POLG_BVDVN ;  Q01499, POLG_BVDVS ;
DR   Q7M438, RNDI_DICDI ;  P81296, RNL2_LENED ;  P80022, RNLE_SOLLC ;
DR   P80196, RNLX_SOLLC ;  P23540, RNMC1_MOMCH;  P19791, RNM_ASPPH  ;
DR   P08056, RNRH_RHINI ;  Q7SID5, RNS11_NICAL;  P42813, RNS1_ARATH ;
DR   O80322, RNS1_PYRPY ;  Q38716, RNS2_ANTHI ;  P42814, RNS2_ARATH ;
DR   P04007, RNS2_NICAL ;  Q40965, RNS2_PYRPY ;  Q01796, RNS2_SOLTU ;
DR   P42815, RNS3_ARATH ;  Q40875, RNS3_PETHY ;  O80323, RNS3_PYRPY ;
DR   Q38717, RNS4_ANTHI ;  Q40966, RNS4_PYRPY ;  P93460, RNS5_PYRPY ;
DR   Q40379, RNS6_NICAL ;  O80324, RNS6_PYRPY ;  Q40381, RNS7_NICAL ;
DR   O80325, RNS7_PYRPY ;  O61887, RNST2_CAEEL;  C0HKG5, RNT2A_MOUSE;
DR   C0HKG6, RNT2B_MOUSE;  P10281, RNT2_ASPOR ;  B8XY56, RNT2_DANRE ;
DR   O00584, RNT2_HUMAN ;  Q7M329, RNT2_PIG   ;  P24657, RNTR_HYPRU ;
DR   Q5AK94, RNY1A_CANAL;  Q5AKB1, RNY1B_CANAL;  Q4WXZ5, RNY1_ASPFU ;
DR   Q6FP42, RNY1_CANGA ;  Q6BHB1, RNY1_DEBHA ;  Q5B3K6, RNY1_EMENI ;
DR   Q75BW5, RNY1_EREGS ;  Q6CRT6, RNY1_KLULA ;  Q6CAV7, RNY1_YARLI ;
DR   Q02933, RNY1_YEAST ;
//