ID   4.8.1.1
DE   L-piperazate synthase.
CA   N(5)-hydroxy-L-ornithine = (3S)-1,2-diazinane-3-carboxylate + H(+) + H2O.
CC   -!- Contains a heme b cofactor.
CC   -!- The enzyme, characterized from the bacterium Kutzneria sp. 744,
CC       is one of very few enzymes known to result in the formation of an N-N
CC       bond.
CC   -!- (3S)-1,2-diazinane-3-carboxylate (piperazate) is known to be
CC       incorporated into assorted secondary products that are produced by
CC       nonribosomal peptide synthetase or nonribosomal peptide
CC       synthetase/polyketide synthase hybrid pathways, such as the
CC       kutznerides, padanamides, himastatins, and sanglifehrins.
//