ID   5.1.1.23
DE   UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase.
AN   UDP-MurNAc-L-Ala-L-Glu epimerase.
CA   ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate = AMP +
CA   diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate.
CC   -!- The enzyme, characterized from the bacterium Xanthomonas oryzae,
CC       catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-
CC       alpha-D-muramoyl-L-alanyl-L-glutamate.
CC   -!- The reaction proceeds only in one direction and involves an
CC       adenylated intermediate.
CC   -!- The combined activity of this enzyme and EC 6.3.2.53 provides an
CC       alternative route for incorporating D-glutamate into peptidoglycan,
CC       replacing the more common combination of EC 5.1.1.3 and EC 6.3.2.9.
DR   C4RJF8, MURL_MICS3 ;  A4X982, MURL_SALTO ;  P0DQD8, MURL_XANOM ;
//