ID   5.3.99.13
DE   4'-phospho-dehydrooxetanocin synthase.
CA   dAMP + S-adenosyl-L-methionine = 4'-phospho-dehydrooxetanocin +
CA   5'-deoxyadenosine + L-methionine + H(+).
CC   -!- The enzyme is a B12-dependent radical SAM (AdoMet) enzyme involved in
CC       the biosynthesis of oxetanocin A.
CC   -!- The enzyme catalyzes an oxidative ring contraction, forming an
CC       oxetane aldehyde.
CC   -!- The reaction requires S-adenosyl-L-methionine, a cobalamin cofactor,
CC       and a reductant (the reductant does not show in the overall reaction
CC       because it is being restored during the cycle).
CC   -!- The reaction is initiated by formation of 5'-deoxyadenosin-5'-yl
CC       radical, which then abstracts a hydrogen atom from C2'.
CC   -!- The enzyme is also able to catalyze the radical mediated,
CC       stereoselective C2'-methylation of dAMP.
DR   O24770, OXSB_PRIMG ;
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