ID   5.4.4.5
DE   9,12-octadecadienoate 8-hydroperoxide 8R-isomerase.
AN   (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((5S,8R,9Z,12Z)-
AN   5,8-dihydroxy-9,12-octadecadienoate-forming).
CA   (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (5S,8R,9Z,12Z)-5,8-
CA   dihydroxyoctadeca-9,12-dienoate.
CC   -!- The bifunctional enzyme from Aspergillus nidulans uses different heme
CC       domains to catalyze two separate reactions.
CC   -!- Linoleic acid is oxidized within the N-terminal heme peroxidase
CC       domain to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate (cf.
CC       EC 1.13.11.60), which is subsequently isomerized to (5S,8R,9Z,12Z)-
CC       5,8-dihydroxyoctadeca-9,12-dienoate within the C-terminal P450 heme
CC       thiolate domain.
DR   B0Y6R2, PPOA_ASPFC ;  Q4WPX2, PPOA_ASPFU ;  Q6RET3, PPOA_EMEND ;
DR   G5EB19, PPOA_EMENI ;
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