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ENZYME

ENZYME entry: EC 5.4.99.19

PURL: https://purl.expasy.org/enzyme/EC/5.4.99.19
Accepted Name
16S rRNA pseudouridine(516) synthase
Alternative Name(s)
16S RNA pseudouridine(516) synthase
16S RNA pseudouridine 516 synthase
16S RNA Psi(516) synthase
Reaction catalysed
uridine(516) in 16S rRNA = pseudouridine(516) in 16S rRNA
Comment(s)
  • The enzyme is specific for uridine(516) in 16S rRNA.
  • In vitro, the enzyme does not modify free 16S rRNA.
  • The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins.
Cross-references
BRENDA5.4.99.19
EC2PDB5.4.99.19
ExplorEnz5.4.99.19
KEGG Ligand Database for Enzyme Nomenclature5.4.99.19
IUBMB Enzyme Nomenclature5.4.99.19
MEDLINEFind literature relating to 5.4.99.19
MetaCyc5.4.99.19
Rhea expert-curated reactions5.4.99.19
UniProtKB/Swiss-Prot
P0AA45, RSUA_ECO57P0AA44, RSUA_ECOL6P0AA43, RSUA_ECOLI
P45124, RSUA_HAEINQ9CPN4, RSUA_PASMUQ9I5J6, RSUA_PSEAE
P65841, RSUA_SALTIP65840, RSUA_SALTYP0AA46, RSUA_SHIFL
Q9KRK5, RSUA_VIBCHQ87QD4, RSUA_VIBPAQ8D8X2, RSUA_VIBVU
Q8ZGM2, RSUA_YERPE

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