ID   5.6.2.3
DE   DNA 5'-3' helicase.
AN   5' to 3' DNA helicase.
AN   replication fork helicase.
AN   replicative DNA helicase.
CA   Couples ATP hydrolysis with the unwinding of duplex DNA at the
CA   replication fork by translocating in the 5'-3' direction. This creates
CA   two antiparallel DNA single strands (ssDNA). The leading ssDNA polymer is
CA   the template for DNA polymerase III holoenzyme which synthesizes a
CA   continuous strand.
CC   -!- The activity is stimulated by DNA polymerase III.
CC   -!- As the lagging ssDNA is created, it becomes coated with S Single-
CC       Stranded DNA Binding protein (SSB).
CC   -!- Once every 500-2000 nucleotides, primase is stimulated by DnaB
CC       helicase to synthesize a primer at the replication fork.
CC   -!- This primer is elongated by the lagging strand half of DNA polymerase
CC       III holoenzyme.
DR   F0NDL2, HELS_SULIR ;  Q974S1, HELS_SULTO ;  Q5ZIW1, PEO1_CHICK ;
DR   Q9VL76, PEO1_DROME ;  Q96RR1, PEO1_HUMAN ;  Q8CIW5, PEO1_MOUSE ;
DR   O34481, RECD2_BACSU;  Q9RT63, RECD2_DEIRA;  P57530, RECD_BUCAI ;
DR   Q8K9A8, RECD_BUCAP ;  Q89AB2, RECD_BUCBP ;  P04993, RECD_ECOLI ;
DR   P45158, RECD_HAEIN ;  A0QS28, RECD_MYCS2 ;  P9WHJ0, RECD_MYCTO ;
DR   P9WHJ1, RECD_MYCTU ;  Q86YA3, ZGRF1_HUMAN;  Q0VGT4, ZGRF1_MOUSE;
//