ID 6.2.1.36 DE 3-hydroxypropionyl-CoA synthase. AN 3-hydroxypropionate--CoA ligase. AN 3-hydroxypropionyl-CoA synthetase (AMP-forming). CA 3-hydroxypropanoate + ATP + CoA = 3-hydroxypropanoyl-CoA + AMP + CA diphosphate. CC -!- Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle, CC an autotrophic CO2 fixation pathway found in some thermoacidophilic CC archaea. CC -!- The enzymes from Metallosphaera sedula and Sulfolobus tokodaii can CC also use propanoate, acrylate, acetate, and butanoate as substrates, CC and are thus different from EC 6.2.1.17, which does not accept CC acetate or butanoate. DR A4YGR1, HPCAS_METS5; Q973W5, HPCAS_SULTO; //