ID   6.2.1.39
DE   [butirosin acyl-carrier protein]--L-glutamate ligase.
AN   [BtrI acyl-carrier protein]--L-glutamate ligase.
CA   (1) holo-[BtrI ACP] + L-glutamate + ATP = gamma-L-glutamyl-[BtrI ACP] +
CA   ADP + phosphate.
CA   (2) 4-aminobutanoyl-[BtrI ACP] + L-glutamate + ATP = 4-(gamma-L-
CA   glutamylamino)butanoyl-[BtrI ACP] + ADP + phosphate + H(+).
CC   -!- Catalyzes two steps in the biosynthesis of the side chain of the
CC       aminoglycoside antibiotics of the butirosin family.
CC   -!- The enzyme adds one molecule of L-glutamate to a dedicated acyl-
CC       carrier protein, and following decarboxylation of the product by
CC       EC 4.1.1.95, adds a second L-glutamate molecule.
DR   Q4H4E7, BTRJ_NIACI ;
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