ID 6.2.1.65 DE salicylate--CoA ligase. CA ATP + CoA + salicylate = 2-hydroxybenzoyl-CoA + AMP + diphosphate. CC -!- The enzyme, characterized from the bacteria Thauera aromatica and CC Streptomyces sp. WA46, participates in a salicylate degradation CC pathway. CC -!- It activates salicylate by its adenylation to CC (2-hydroxybenzoyl)adenylate, followed by the transfer of the CC activated compound to coenzyme A. DR Q7X279, SDGA_STRSQ ; //