ID 6.2.1.73 DE L-tryptophan--[L-tryptophyl-carrier protein] ligase. CA holo-[peptidyl-carrier protein] + L-tryptophan + ATP = L-tryptophyl- CA [peptidyl-carrier protein] + AMP + diphosphate. CC -!- The adenylation domain of the enzyme catalyzes the activation of CC L-tryptophan to (L-tryptophyl)adenylate, followed by the transfer of CC the activated compound to the free thiol of a phosphopantetheine arm CC of a peptidyl-carrier protein domain. CC -!- The peptidyl-carrier protein domain may be part of the same protein, CC or of a different protein. CC -!- This activity is often found as part of a larger non-ribosomal CC peptide synthase. //