ID 6.2.1.76 DE malonate--CoA ligase. CA ATP + CoA + malonate = AMP + diphosphate + malonyl-CoA. CC -!- The enzyme, found in mitochondria, detoxifies malonate, which is a CC potent inhibitor of mitochondrial respiration, and provides malonyl- CC CoA to the mitochondrial fatty acid biosynthesis pathway. CC -!- Formerly EC 6.2.1.n3. DR Q8H151, AAE13_ARATH; Q58DN7, ACSF3_BOVIN; Q4G176, ACSF3_HUMAN; DR Q3URE1, ACSF3_MOUSE; Q6GLK6, ACSF3_XENLA; //