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ENZYME

ENZYME entry: EC 6.2.1.78

PURL: https://purl.expasy.org/enzyme/EC/6.2.1.78
Accepted Name
(3R)-beta-phenylalanine--CoA ligase
Alternative Name(s)
beta-phenylalanine coenzyme A ligase
Reaction catalysed
(3R)-beta-phenylalanine + ATP + CoA = (3R)-3-amino-3-phenylpropanoyl-CoA + AMP + diphosphate
Comment(s)
  • The enzyme, characterized from the fungus Penicillium chrysogenum, acts on (3R)-beta-phenylalanine and has slight activity on some other amino acids including (3S)-beta-phenylalanine.
  • It also acts on medium-chain-length alkanoic acids as EC 6.2.1.2.
  • In taxol-producing trees the enzyme is involved in taxol biosynthesis.
Cross-references
Rhea expert-curated reactions6.2.1.78
ExplorEnz6.2.1.78
IUBMB Enzyme Nomenclature6.2.1.78
UniProtKB/Swiss-Prot
A0A0E3JHZ7, PCL_TAXBAA0AA38KJ08, PCL_TAXCH
BRENDA6.2.1.78
MetaCyc6.2.1.78
KEGG Ligand Database for Enzyme Nomenclature6.2.1.78
MEDLINEFind literature relating to 6.2.1.78

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-