ID 6.3.2.39 DE Aerobactin synthase. CA ATP + N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine + N(6)-acetyl-N(6)- CA hydroxy-L-lysine = AMP + diphosphate + aerobactin. CF Mg(2+). CC -!- Requires Mg(2+). CC -!- The enzyme is involved in the biosynthesis of aerobactin, CC a dihydroxamate siderophore. CC -!- It belongs to a class of siderophore synthases known as type CC C nonribosomal peptide synthase-independent synthases (NIS). CC -!- Type C enzymes are responsible for the formation of amide or ester CC bonds between a variety of substrates and a prochiral carboxyl group CC of a citrate molecule that is already linked to a different moiety at CC its other prochiral carboxyl group. CC -!- The enzyme is believed to form an adenylate intermediate prior to CC ligation. DR Q47318, IUCC_ECOLX ; Q76BS5, IUCC_VIBMI ; //