ID   6.3.2.39
DE   aerobactin synthase.
CA   N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine + N(6)-acetyl-N(6)-hydroxy-
CA   L-lysine + ATP = aerobactin + AMP + diphosphate + H(+).
CC   -!- Requires Mg(2+).
CC   -!- The enzyme is involved in the biosynthesis of aerobactin,
CC       a dihydroxamate siderophore.
CC   -!- It belongs to a class of siderophore synthases known as type
CC       C nonribosomal peptide synthase-independent synthases (NIS).
CC   -!- Type C enzymes are responsible for the formation of amide or ester
CC       bonds between a variety of substrates and a prochiral carboxyl group
CC       of a citrate molecule that is already linked to a different moiety at
CC       its other prochiral carboxyl group.
CC   -!- The enzyme is believed to form an adenylate intermediate prior to
CC       ligation.
CC   -!- Formerly EC 6.3.2.27.
DR   Q47318, IUCC_ECOLX ;  Q76BS5, IUCC_VIBMI ;
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