ID 6.3.2.43 DE [amino-group carrier protein]--L-2-aminoadipate ligase. AN AAA--LysW ligase. AN alpha-aminoadipate-lysW ligase. CA [amino-group carrier protein]-C-terminal-L-glutamate + ATP + L-2- CA aminoadipate = [amino-group carrier protein]-C-terminal-N-(1,4- CA dicarboxybutan-1-yl)-L-glutamine + ADP + H(+) + phosphate. CC -!- The enzymes from the thermophilic bacterium Thermus thermophilus and CC the thermophilic archaea Sulfolobus acidocaldarius and Sulfolobus CC tokodaii protect the amino group of L-2-aminoadipate by conjugation CC to the carrier protein LysW. CC -!- This reaction is part of the lysine biosynthesis pathway in these CC organisms. CC -!- Formerly EC 6.3.2.n4. DR Q7SI95, LYSX_SACS2 ; Q4JAP9, LYSX_SULAC ; Q976J9, LYSX_SULTO ; DR Q5SH23, LYSX_THET8 ; //