ID 6.3.2.54 DE L-2,3-diaminopropanoate--citrate ligase. AN 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate synthtase. CA (S)-2,3-diaminopropanoate + ATP + citrate = 2-[(L-alanin-3- CA ylcarbamoyl)methyl]-2-hydroxybutanedioate + AMP + diphosphate. CC -!- Requires Mg(2+). CC -!- The enzyme, characterized from the bacterium Staphylococcus aureus, CC is involved in the biosynthesis of the siderophore staphyloferrin B. CC -!- It belongs to a class of siderophore synthases known as type A CC nonribosomal peptide synthase-independent synthases (NIS). CC -!- Type A NIS enzymes are responsible for the formation of amide or CC ester bonds between polyamines or amino alcohols and a prochiral CC carboxyl group of citrate. CC -!- The enzyme forms a citrate adenylate intermediate prior to ligation. DR Q2G1M9, SBNE_STAA8 ; //