ID 6.3.3.4 DE (carboxyethyl)arginine beta-lactam-synthase. AN beta-lactam synthetase. CA ATP + N(2)-(2-carboxyethyl)-L-arginine = AMP + deoxyamidinoproclavaminate CA + diphosphate + H(+). CC -!- Forms part of the pathway for the biosythesis of the beta-lactamase CC inhibitor clavulanate in Streptomyces clavuligerus. CC -!- It has been proposed that L-N(2)-(2-carboxyethyl)arginine is first CC converted into an acyl-AMP by reaction with ATP and loss of CC diphosphate, and that the beta-lactam ring is then formed by the CC intramolecular attack of the beta-nitrogen on the activated carboxy CC group. DR P0DJQ7, BLS_STRCL ; //