ID   6.3.4.18
DE   5-(carboxyamino)imidazole ribonucleotide synthase.
AN   N(5)-CAIR synthetase.
AN   N(5)-carboxyaminoimidazole ribonucleotide synthetase.
CA   5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate =
CA   5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) +
CA   phosphate.
CC   -!- In Escherichia coli, this enzyme, along with EC 5.4.99.18,
CC       is required to carry out the single reaction catalyzed by EC 4.1.1.21
CC       in vertebrates.
CC   -!- Carboxyphosphate is the putative acyl phosphate intermediate.
CC   -!- Involved in the late stages of purine biosynthesis.
DR   Q5E1R3, PURK_ALIF1 ;  O66608, PURK_AQUAE ;  P12045, PURK_BACSU ;
DR   P52559, PURK_BRUME ;  Q44678, PURK_CORAM ;  P09029, PURK_ECOLI ;
DR   P43850, PURK_HAEIN ;  P65899, PURK_MYCBO ;  P46701, PURK_MYCLE ;
DR   P9WHL8, PURK_MYCTO ;  P9WHL9, PURK_MYCTU ;  P72158, PURK_PSEAE ;
DR   O06457, PURK_SACS2 ;  Q5HH19, PURK_STAAC ;  Q99V32, PURK_STAAM ;
DR   Q7A695, PURK_STAAN ;  Q6GI19, PURK_STAAR ;  Q6GAE8, PURK_STAAS ;
DR   Q8NX94, PURK_STAAW ;  Q5HQA5, PURK_STAEQ ;  Q8CPP2, PURK_STAES ;
DR   Q4L574, PURK_STAHJ ;  Q49WI9, PURK_STAS1 ;  Q54975, PURK_SYNE7 ;
DR   P74724, PURK_SYNY3 ;  Q9KVT8, PURK_VIBCH ;  Q87KE0, PURK_VIBPA ;
DR   Q8DDD8, PURK_VIBVU ;  Q7MGL1, PURK_VIBVY ;
//