ID 6.3.5.12 DE Ni-sirohydrochlorin a,c-diamide synthase. CA 2 ATP + 2 H2O + 2 L-glutamine + Ni-sirohydrochlorin = 2 ADP + 2 H(+) + CA 2 L-glutamate + Ni-sirohydrochlorin a,c-diamide + 2 phosphate. CC -!- The enzyme, studied from the methanogenic archaeon Methanosarcina CC acetivorans, participates in the biosynthesis of the nickel- CC containing tetrapyrrole cofactor coenzyme F430, which is required by CC EC 2.8.4.1. DR Q8TK00, CBIA_METAC ; Q46FL0, CBIA_METBF ; Q58816, CBIA_METJA ; DR A4FW46, CBIA_METM5 ; A6VH63, CBIA_METM7 ; A5UMJ2, CBIA_METS3 ; DR Q2NHQ3, CBIA_METST ; O27509, CBIA_METTH ; A6UQC1, CBIA_METVS ; //