ID 6.3.5.13 DE lipid II isoglutaminyl synthase (glutamine-hydrolyzing). CA ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D- CA Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H2O + L-glutamine = CA ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala- CA D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + L-glutamate + CA phosphate. CC -!- The enzyme complex, found in Gram-positive bacteria, consists of two CC subunits. CC -!- A glutaminase subunit (cf. EC 3.5.1.2) produces an ammonia molecule CC that is channeled to a ligase subunit, which adds it to the activated CC D-glutamate residue of lipid II, converting it to an isoglutamine CC residue. DR A0A0H2WZ38, GATD_STAAC ; A0A0H3JN63, GATD_STAAN ; Q8DNZ8, GATD_STRR6 ; DR A0A0H2WZQ7, MURT_STAAC ; A0A0H3JUU7, MURT_STAAN ; Q8DNZ9, MURT_STRR6 ; //