ID 6.4.1.11 DE polyporic acid synthase. CA 2 3-phenylpyruvate + 2 ATP = polyporic acid + 2 AMP + 2 diphosphate + CA H(+). CC -!- Requires Mg(2+). CC -!- The enzyme, found in mushrooms of the Basidiomycota and Ascomycota CC phyla, is a non-ribosomal peptide synthase-like enzyme comprising CC three domains - an adelylation (A) domain, an ayl-carrier protein CC (ACP) domain, and a thioesterase (TE) domain. CC -!- The enzyme activates 3-phenyl-2-oxopropanoate by adenylation and CC catalyzes the dimerization/cyclization of two such molecules to form CC polyporic acid. CC -!- Polyporic acid is a precursor for assorted metabolites produced by CC the fungi, such as the corticins. //