ID   7.1.1.12
DE   succinate dehydrogenase (electrogenic, proton-motive force generating).
CA   a menaquinone + 2 H(+)(out) + succinate = a menaquinol + fumarate +
CA   2 H(+)(in).
CC   -!- The enzyme is very similar to EC 1.3.5.1 but differs by containing
CC       two heme molecules (located in the membrane anchor component) in
CC       addition to FAD and three iron-sulfur clusters.
CC   -!- Unlike EC 1.3.5.1, this enzyme catalyzes an electrogenic reaction,
CC       enabled by electron-bifurcation via the heme molecules.
CC   -!- In the direction of succinate oxidation by menaquinone, which is
CC       endergonic, the reaction is driven by the transmembrane
CC       electrochemical proton potential.
CC   -!- In the direction of fumarate reduction, the electrogenic electron
CC       transfer reaction is compensated by transmembrane proton transfer
CC       pathway known as the E-pathway, which results in overall
CC       electroneutrality.
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