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ENZYME entry: EC 7.1.2.1

Accepted Name
P-type H(+)-exporting transporter.
Alternative Name(s)
H(+)-transporting ATPase.
Proton transport ATPase.
Proton-translocating P-type ATPase.
Reaction catalysed
ATP + H(2)O + H(+)(Side 1) <=> ADP + phosphate + H(+)(Side 2)
Cofactor(s)
Mg(2+).
Comment(s)
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme occurs in protozoa, fungi and plants, and generates an electrochemical potential gradient of protons across the plasma membrane.
  • Formerly EC 3.6.1.35 and EC 3.6.3.6.
Cross-references
PROSITEPDOC00139
BRENDA7.1.2.1
EC2PDB7.1.2.1
ExplorEnz7.1.2.1
PRIAM enzyme-specific profiles7.1.2.1
KEGG Ligand Database for Enzyme Nomenclature7.1.2.1
IUBMB Enzyme Nomenclature7.1.2.1
IntEnz7.1.2.1
MEDLINEFind literature relating to 7.1.2.1
MetaCyc7.1.2.1
Rhea expert-curated reactions7.1.2.1
UniProtKB/Swiss-Prot
P11718, ATXA_LEIDO;  P12522, ATXB_LEIDO;  Q43128, PMA10_ARATH;  
Q9LV11, PMA11_ARATH;  Q07421, PMA1_AJECA;  P20649, PMA1_ARATH;  
P28877, PMA1_CANAX;  P54679, PMA1_DICDI;  P54210, PMA1_DUNAC;  
P54211, PMA1_DUNBI;  P49380, PMA1_KLULA;  P07038, PMA1_NEUCR;  
Q08435, PMA1_NICPL;  Q7XPY2, PMA1_ORYSJ;  P09627, PMA1_SCHPO;  
P22180, PMA1_SOLLC;  P83970, PMA1_WHEAT;  P05030, PMA1_YEAST;  
P24545, PMA1_ZYGRO;  P19456, PMA2_ARATH;  P28876, PMA2_SCHPO;  
P23980, PMA2_SOLLC;  P19657, PMA2_YEAST;  P20431, PMA3_ARATH;  
Q08436, PMA3_NICPL;  Q9SU58, PMA4_ARATH;  Q03194, PMA4_NICPL;  
Q9SJB3, PMA5_ARATH;  Q9SH76, PMA6_ARATH;  Q9LY32, PMA7_ARATH;  
Q9M2A0, PMA8_ARATH;  Q42556, PMA9_ARATH;  Q7M290, PMA_AVESA;  

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