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ENZYME entry: EC 7.1.3.1

Accepted Name
H(+)-exporting diphosphatase.
Alternative Name(s)
H(+)-PPase.
Hydrogen-translocating pyrophosphatase.
Proton-pumping diphosphatase.
Proton-pumping pyrophosphatase.
Vacuolar H(+)-pyrophosphatase.
Reaction catalysed
Diphosphate + H(2)O + H(+)(Side 1) <=> 2 phosphate + H(+)(Side 2)
Comment(s)
  • This enzyme, found in plants and fungi, couples the energy from diphosphate hydrolysis to active proton translocation across the tonoplast into the vacuole.
  • The enzyme acts cooperatively with cytosolic soluble diphosphatases to regulate the cytosolic diphosphate level.
Cross-references
BRENDA7.1.3.1
EC2PDB7.1.3.1
ExplorEnz7.1.3.1
PRIAM enzyme-specific profiles7.1.3.1
KEGG Ligand Database for Enzyme Nomenclature7.1.3.1
IUBMB Enzyme Nomenclature7.1.3.1
IntEnz7.1.3.1
MEDLINEFind literature relating to 7.1.3.1
MetaCyc7.1.3.1
UniProtKB/Swiss-Prot
P31414, AVP1_ARATH;  Q56ZN6, AVP2_ARATH;  Q9FWR2, AVPX_ARATH;  
Q06572, AVP_HORVU;  P21616, AVP_VIGRR;  Q93AR8, HPPA1_MYCDI;  
Q93AS0, HPPA1_RHILT;  Q8TJA8, HPPA2_METAC;  Q8PYZ7, HPPA2_METMA;  
Q2RLE0, HPPA2_MOOTA;  Q93AR9, HPPA2_MYCDI;  Q93AS1, HPPA2_RHILT;  
Q8UG67, HPPA_AGRFC;  Q8VNU8, HPPA_ALLVI;  Q8VRZ1, HPPA_ANAMA;  
Q89K83, HPPA_BRADU;  Q8YGH4, HPPA_BRUME;  Q8G1E6, HPPA_BRUSU;  
Q8RCX1, HPPA_CALS4;  Q3AFC6, HPPA_CARHZ;  Q9A8J0, HPPA_CAUVC;  
Q8VNW3, HPPA_CHLAA;  Q8KDT8, HPPA_CHLTE;  Q82TF3, HPPA_NITEU;  
Q8VRZ2, HPPA_OCHA4;  Q8ZWI8, HPPA_PYRAE;  Q983A3, HPPA_RHILO;  
Q8VRZ3, HPPA_RHIME;  P60363, HPPA_RHOPA;  Q8KY01, HPPA_RHOPL;  
O68460, HPPA_RHORT;  Q82EJ8, HPPA_STRAW;  Q9X913, HPPA_STRCO;  
Q8PH20, HPPA_XANAC;  Q8P5M6, HPPA_XANCP;  

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