ID 7.2.4.5 DE glutaconyl-CoA decarboxylase. AN 4-carboxybut-2-enoyl-CoA carboxy-lyase. AN glutaconyl coenzyme A decarboxylase. AN pent-2-enoyl-CoA carboxy-lyase. CA (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + CA Na(+)(out). CC -!- The enzyme from the bacterium Acidaminococcus fermentans is a CC biotinyl-protein, requires Na(+), and acts as a sodium pump. CC -!- Prior to the Na(+)-dependent decarboxylation, the carboxylate is CC transferred to biotin in a Na(+)-independent manner. CC -!- The conserved lysine, to which biotin forms an amide bond, is located CC 34 amino acids before the C-terminus, flanked on both sides by two CC methionine residues, which are conserved in every biotin-dependent CC enzyme. CC -!- Formerly EC 4.1.1.70. DR Q06700, GCDA_ACIFV ; Q9ZAA6, GCDB_ACIFV ; Q9ZAA7, GCDC_ACIFV ; DR Q9ZAA8, GCDD_ACIFV ; //