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ENZYME entry: EC

Accepted Name
arsenite-transporting ATPase.
Alternative Name(s)
arsenical pump-driving ATPase.
arsenical resistance ATPase.
arsenite-translocating ATPase.
Reaction catalysed
arsenite(in) + ATP + H2O <=> ADP + arsenite(out) + H(+) + phosphate
  • This bacterial transporter does not belong to the ABC superfamily, and instead is a member of its own family, referred to as the Ars family.
  • The enzyme usually contains two subunits where one (with 12 membrane- spanning segments) forms the 'channel' part and the other (occurring in pairs peripherally to the membrane) contains the ATP-binding site.
  • It forms an arsenite efflux pump that removes arsenite from the cytoplasm, and can also remove antimonite anions.
  • Formerly EC
PRIAM enzyme-specific profiles7.3.2.7
KEGG Ligand Database for Enzyme Nomenclature7.3.2.7
IUBMB Enzyme Nomenclature7.3.2.7
MEDLINEFind literature relating to
Rhea expert-curated reactions7.3.2.7
O66908, ARSA1_AQUAE;  P08690, ARSA1_ECOLX;  O66674, ARSA2_AQUAE;  
P52145, ARSA2_ECOLX;  O50593, ARSA_ACIMA;  Q46366, ARSA_CHLTE;  
O52027, ARSA_HALSA;  Q58542, ARSA_METJA;  O27555, ARSA_METTH;  
Q46465, ARSA_PROVB;  Q55794, ARSA_SYNY3;  

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