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ENZYME

ENZYME entry: EC 7.4.2.10

PURL: https://purl.expasy.org/enzyme/EC/7.4.2.10
Accepted Name
ABC-type glutathione transporter
Alternative Name(s)
glutathione ABC transporter
glutathione transporting ATPase
Reaction catalysed
glutathione(out) + ATP + H2O = glutathione(in) + ADP + phosphate + H(+)
Comment(s)
  • A prokaryotic ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • The enzyme from the bacterium Escherichia coli is a heterotrimeric complex that interacts with an extracytoplasmic substrate binding protein to mediate the uptake of glutathione.
Cross-references
BRENDA7.4.2.10
EC2PDB7.4.2.10
ExplorEnz7.4.2.10
KEGG Ligand Database for Enzyme Nomenclature7.4.2.10
IUBMB Enzyme Nomenclature7.4.2.10
MEDLINEFind literature relating to 7.4.2.10
MetaCyc7.4.2.10
Rhea expert-curated reactions7.4.2.10
UniProtKB/Swiss-Prot
Q8X6W1, GSIA_ECO57A1A967, GSIA_ECOK1Q0TJM0, GSIA_ECOL5
Q8FJL0, GSIA_ECOL6P75796, GSIA_ECOLIQ1RE96, GSIA_ECOUT
Q6D3A9, GSIA_PECASQ57RB2, GSIA_SALCHQ5PGP3, GSIA_SALPA
Q8Z864, GSIA_SALTIQ8ZQM4, GSIA_SALTYQ323W5, GSIA_SHIBS
Q32IB5, GSIA_SHIDSQ0T6D3, GSIA_SHIF8Q83LT3, GSIA_SHIFL
Q3Z3V4, GSIA_SHISS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-