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ENZYME entry: EC 7.4.2.10

Accepted Name
ABC-type glutathione transporter.
Alternative Name(s)
Glutathione ABC transporter.
Glutathione transporting ATPase.
Reaction catalysed
ATP + H(2)O + glutathione-[glutathione-binding protein](Side 1) <=> ADP + phosphate + glutathione(Side 2) + [glutathione-binding protein](Side 1)
Comment(s)
  • A prokaryotic ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • The enzyme from the bacterium Escherichia coli is a heterotrimeric complex that interacts with an extracytoplasmic substrate binding protein to mediate the uptake of glutathione.
Cross-references
BRENDA7.4.2.10
EC2PDB7.4.2.10
ExplorEnz7.4.2.10
PRIAM enzyme-specific profiles7.4.2.10
KEGG Ligand Database for Enzyme Nomenclature7.4.2.10
IUBMB Enzyme Nomenclature7.4.2.10
IntEnz7.4.2.10
MEDLINEFind literature relating to 7.4.2.10
MetaCyc7.4.2.10
UniProtKB/Swiss-Prot
Q8X6W1, GSIA_ECO57;  A1A967, GSIA_ECOK1;  Q0TJM0, GSIA_ECOL5;  
Q8FJL0, GSIA_ECOL6;  P75796, GSIA_ECOLI;  Q1RE96, GSIA_ECOUT;  
Q6D3A9, GSIA_PECAS;  Q57RB2, GSIA_SALCH;  Q5PGP3, GSIA_SALPA;  
Q8Z864, GSIA_SALTI;  Q8ZQM4, GSIA_SALTY;  Q323W5, GSIA_SHIBS;  
Q32IB5, GSIA_SHIDS;  Q0T6D3, GSIA_SHIF8;  Q83LT3, GSIA_SHIFL;  
Q3Z3V4, GSIA_SHISS;  

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