ID   7.4.2.14
DE   ABC-type antigen peptide transporter.
CA   a peptide antigen(in) + ATP + H2O = a peptide antigen(out) + ADP + H(+) +
CA   phosphate.
CC   -!- An ATP-binding cassette (ABC) type transporter, characterized by the
CC       presence of two similar ATP-binding domains/proteins and two integral
CC       membrane domains/proteins.
CC   -!- Does not undergo phosphorylation during the transport process.
CC   -!- This entry describes vertebrate transporters involved in the
CC       transport of antigens from the cytoplasm to the endoplasmic reticulum
CC       for association with major histocompatibility complex (MHC) class I
CC       molecules.
CC   -!- The substrates are generated mainly from degradation of cytosolic
CC       proteins by the proteasome.
DR   Q28433, TAP1_GORGO ;  Q03518, TAP1_HUMAN ;  P21958, TAP1_MOUSE ;
DR   P36370, TAP1_RAT   ;  Q03519, TAP2_HUMAN ;  P36371, TAP2_MOUSE ;
DR   P36372, TAP2_RAT   ;
//