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ENZYME entry: EC 7.4.2.3

Accepted Name
Mitochondrial protein-transporting ATPase.
Reaction catalysed
ATP + H(2)O + mitochondrial-protein(Side 1) <=> ADP + phosphate + mitochondrial-protein(Side 2)
Comment(s)
  • A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase involved in the transport of proteins or preproteins into mitochondria using the TIM protein complex.
  • TIM is the protein transport machinery of the mitochondrial inner membrane that contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
  • Formerly EC 3.6.3.51.
Cross-references
BRENDA7.4.2.3
EC2PDB7.4.2.3
ExplorEnz7.4.2.3
PRIAM enzyme-specific profiles7.4.2.3
KEGG Ligand Database for Enzyme Nomenclature7.4.2.3
IUBMB Enzyme Nomenclature7.4.2.3
IntEnz7.4.2.3
MEDLINEFind literature relating to 7.4.2.3
MetaCyc7.4.2.3
Rhea expert-curated reactions7.4.2.3

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-