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ENZYME entry: EC 7.4.2.5

Accepted Name
Bacterial ABC-type protein transporter.
Alternative Name(s)
Peptide-transporting ATPase.
Reaction catalysed
ATP + H(2)O + protein(Side 1) <=> ADP + phosphate + protein(Side 2)
Comment(s)
  • An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • This entry stands for a family of bacterial enzymes that are dedicated to the secretion of one or several closely related proteins belonging to the toxin, protease and lipase families.
  • Examples from Gram-negative bacteria include alpha-hemolysin, cyclolysin, colicin V and siderophores, while examples from Gram- positive bacteria include bacteriocin, subtilin, competence factor and pediocin.
  • Formerly EC 3.6.3.43.
Cross-references
PROSITEPDOC00185 ; PDOC50990
BRENDA7.4.2.5
EC2PDB7.4.2.5
ExplorEnz7.4.2.5
PRIAM enzyme-specific profiles7.4.2.5
KEGG Ligand Database for Enzyme Nomenclature7.4.2.5
IUBMB Enzyme Nomenclature7.4.2.5
IntEnz7.4.2.5
MEDLINEFind literature relating to 7.4.2.5
MetaCyc7.4.2.5
UniProtKB/Swiss-Prot
Q93FH2, LKB13_MANHA;  P0C087, LKB14_MANHA;  Q93FH3, LKB16_MANHA;  
P16532, LKB1A_MANHA;  Q93FH6, LKB1B_MANHA;  Q93FH0, LKB2A_MANHA;  
Q93FG6, LKB2B_MANHA;  P0C086, LKTB7_MANHA;  Q933E0, LKTB_BIBTR;  
Q933I3, LKTB_MANGL;  P55122, LKTB_PASSP;  P23702, LTXB_AGGAC;  
Q9RCG7, PAXB_PASAE;  

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