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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 7.4.2.8

Accepted Name
Protein-secreting ATPase.
Reaction catalysed
ATP + H(2)O + cellular protein(Side 1) <=> ADP + phosphate + cellular protein(Side 2)
Comment(s)
  • A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase that is involved in protein transport.
  • There are several families of enzymes included here, e.g. ATP- hydrolyzing enzymes of the general secretory pathway (Sec or Type II), of the virulence-related secretory pathway (Type III) and of the conjugal DNA-protein transfer pathway (Type IV).
  • Type II enzymes occur in bacteria, archaea and eucarya, whereas type III and type IV enzymes occur in bacteria where they form components of a multi-subunit complex.
  • Formerly EC 3.6.3.50.
Cross-references
BRENDA7.4.2.8
EC2PDB7.4.2.8
ExplorEnz7.4.2.8
PRIAM enzyme-specific profiles7.4.2.8
KEGG Ligand Database for Enzyme Nomenclature7.4.2.8
IUBMB Enzyme Nomenclature7.4.2.8
IntEnz7.4.2.8
MEDLINEFind literature relating to 7.4.2.8
MetaCyc7.4.2.8

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-