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ENZYME

ENZYME entry: EC 7.5.2.5

PURL: https://purl.expasy.org/enzyme/EC/7.5.2.5
Accepted Name
ABC-type lipopolysaccharide transporter
Alternative Name(s)
lipopolysaccharide-transporting ATPase
lipopolysaccharide transport system
Reaction catalysed
ATP + H2O + lipopolysaccharideSide 1 = ADP + phosphate + lipopolysaccharideSide 2
Comment(s)
  • An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • Does not undergo phosphorylation during the transport process.
  • The enzyme, characterized from the bacterium Escherichia coli, functions as part of the lipopolysaccharide (LPS) export system, a seven protein system that translocates LPS from the inner- to the outer membrane.
  • The ATPase activity in this system is implicated in releasing LPS from the inner membrane.
  • Formerly EC 3.6.3.39.
Cross-references
BRENDA7.5.2.5
EC2PDB7.5.2.5
ExplorEnz7.5.2.5
KEGG Ligand Database for Enzyme Nomenclature7.5.2.5
IUBMB Enzyme Nomenclature7.5.2.5
MEDLINEFind literature relating to 7.5.2.5
MetaCyc7.5.2.5
Rhea expert-curated reactions7.5.2.5
UniProtKB/Swiss-Prot
Q0P9C4, PGLK_CAMJE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.5.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-