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ENZYME entry: EC

Accepted Name
ABC-type thiamine transporter.
Alternative Name(s)
Thiamine ABC transporter.
Thiamine ABC transporter.
Thiamine transporting ATPase.
Thiamine transporting ATPase.
Reaction catalysed
ATP + H(2)O + thiamine-[thiamine-binding protein](Side 1) <=> ADP + phosphate + thiamine(Side 2) + [thiamine-binding protein](Side 1)
  • ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • The enzyme, characterized from the bacterium Salmonella typhimurium, is a heterodimeric complex that interacts with an extracytoplasmic substrate binding protein and functions to import thiamine, thiamine monophosphate and thiamine diphosphate.
PRIAM enzyme-specific profiles7.6.2.15
KEGG Ligand Database for Enzyme Nomenclature7.6.2.15
IUBMB Enzyme Nomenclature7.6.2.15
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