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ENZYME entry: EC 7.6.2.15

Accepted Name
ABC-type thiamine transporter.
Alternative Name(s)
Thiamine ABC transporter.
Thiamine ABC transporter.
Thiamine transporting ATPase.
Thiamine transporting ATPase.
Reaction catalysed
ATP + H(2)O + thiamine-[thiamine-binding protein](Side 1) <=> ADP + phosphate + thiamine(Side 2) + [thiamine-binding protein](Side 1)
Comment(s)
  • ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • The enzyme, characterized from the bacterium Salmonella typhimurium, is a heterodimeric complex that interacts with an extracytoplasmic substrate binding protein and functions to import thiamine, thiamine monophosphate and thiamine diphosphate.
Cross-references
BRENDA7.6.2.15
EC2PDB7.6.2.15
ExplorEnz7.6.2.15
PRIAM enzyme-specific profiles7.6.2.15
KEGG Ligand Database for Enzyme Nomenclature7.6.2.15
IUBMB Enzyme Nomenclature7.6.2.15
IntEnz7.6.2.15
MEDLINEFind literature relating to 7.6.2.15
MetaCyc7.6.2.15
Rhea expert-curated reactions7.6.2.15
UniProtKB/Swiss-Prot
Q8UBY6, THIQ_AGRFC;  Q5E882, THIQ_ALIF1;  Q2YLW6, THIQ_BRUA2;  
Q57BC2, THIQ_BRUAB;  Q8YJ04, THIQ_BRUME;  Q8FYU9, THIQ_BRUSU;  
Q11D92, THIQ_CHESB;  Q8XA06, THIQ_ECO57;  Q0TLS2, THIQ_ECOL5;  
Q8FL82, THIQ_ECOL6;  P31548, THIQ_ECOLI;  Q1RGD0, THIQ_ECOUT;  
Q7VP69, THIQ_HAEDU;  Q4QLQ1, THIQ_HAEI8;  P44986, THIQ_HAEIN;  
Q0I354, THIQ_HAES1;  Q28VL7, THIQ_JANSC;  Q65SC9, THIQ_MANSM;  
Q9CNP9, THIQ_PASMU;  Q6D0F3, THIQ_PECAS;  Q7N8V0, THIQ_PHOLL;  
Q6LV32, THIQ_PHOPR;  Q98FA5, THIQ_RHILO;  Q92L31, THIQ_RHIME;  
Q3IY12, THIQ_RHOS4;  Q1GCR8, THIQ_RUEST;  Q57TF5, THIQ_SALCH;  
Q5PDF8, THIQ_SALPA;  Q8Z9I6, THIQ_SALTI;  Q8ZRV2, THIQ_SALTY;  
Q326G9, THIQ_SHIBS;  Q32K28, THIQ_SHIDS;  Q0T8D1, THIQ_SHIF8;  
Q83MG3, THIQ_SHIFL;  Q3Z5U5, THIQ_SHISS;  Q2NVW9, THIQ_SODGM;  
Q9KP42, THIQ_VIBCH;  Q87SV4, THIQ_VIBPA;  Q8DE95, THIQ_VIBVU;  
Q7MPC5, THIQ_VIBVY;  Q1C1Y5, THIQ_YERPA;  Q0WJE4, THIQ_YERPE;  
Q1CMQ3, THIQ_YERPN;  Q66EN1, THIQ_YERPS;  

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