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ENZYME

ENZYME entry: EC 7.6.2.15

PURL: https://purl.expasy.org/enzyme/EC/7.6.2.15
Accepted Name
ABC-type thiamine transporter
Alternative Name(s)
thiamine ABC transporter
thiamine transporting ATPase
Reaction catalysed
thiamine(out) + ATP + H2O = thiamine(in) + ADP + phosphate + H(+)
Comment(s)
  • ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • The enzyme, characterized from the bacterium Salmonella typhimurium, is a heterodimeric complex that interacts with an extracytoplasmic substrate binding protein and functions to import thiamine, thiamine monophosphate and thiamine diphosphate.
Cross-references
BRENDA7.6.2.15
EC2PDB7.6.2.15
ExplorEnz7.6.2.15
KEGG Ligand Database for Enzyme Nomenclature7.6.2.15
IUBMB Enzyme Nomenclature7.6.2.15
MEDLINEFind literature relating to 7.6.2.15
MetaCyc7.6.2.15
Rhea expert-curated reactions7.6.2.15
UniProtKB/Swiss-Prot
Q8UBY6, THIQ_AGRFCQ5E882, THIQ_ALIF1Q2YLW6, THIQ_BRUA2
Q57BC2, THIQ_BRUABQ8YJ04, THIQ_BRUMEQ8FYU9, THIQ_BRUSU
Q3IY12, THIQ_CERS4Q11D92, THIQ_CHESBQ8XA06, THIQ_ECO57
Q0TLS2, THIQ_ECOL5Q8FL82, THIQ_ECOL6P31548, THIQ_ECOLI
Q1RGD0, THIQ_ECOUTQ7VP69, THIQ_HAEDUQ4QLQ1, THIQ_HAEI8
P44986, THIQ_HAEINQ0I354, THIQ_HISS1Q28VL7, THIQ_JANSC
Q65SC9, THIQ_MANSMQ9CNP9, THIQ_PASMUQ6D0F3, THIQ_PECAS
Q7N8V0, THIQ_PHOLLQ6LV32, THIQ_PHOPRQ98FA5, THIQ_RHILO
Q92L31, THIQ_RHIMEQ1GCR8, THIQ_RUESTQ57TF5, THIQ_SALCH
Q5PDF8, THIQ_SALPAQ8Z9I6, THIQ_SALTIQ8ZRV2, THIQ_SALTY
Q326G9, THIQ_SHIBSQ32K28, THIQ_SHIDSQ0T8D1, THIQ_SHIF8
Q83MG3, THIQ_SHIFLQ3Z5U5, THIQ_SHISSQ2NVW9, THIQ_SODGM
Q9KP42, THIQ_VIBCHQ87SV4, THIQ_VIBPAQ8DE95, THIQ_VIBVU
Q7MPC5, THIQ_VIBVYQ1C1Y5, THIQ_YERPAQ0WJE4, THIQ_YERPE
Q1CMQ3, THIQ_YERPNQ66EN1, THIQ_YERPS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.6.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-