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ENZYME entry: EC 7.6.2.4

Accepted Name
ABC-type fatty-acyl-CoA transporter.
Alternative Name(s)
Fatty-acyl-CoA-transporting ATPase.
Reaction catalysed
ATP + H(2)O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2)
Comment(s)
  • An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • Does not undergo phosphorylation during the transport process.
  • An animal and yeast enzyme that transports fatty acyl CoA into and out of peroxisomes.
  • In humans, it is associated with Zellweger's syndrome.
  • Formerly EC 3.6.3.47.
Cross-references
PROSITEPDOC00185
BRENDA7.6.2.4
EC2PDB7.6.2.4
ExplorEnz7.6.2.4
PRIAM enzyme-specific profiles7.6.2.4
KEGG Ligand Database for Enzyme Nomenclature7.6.2.4
IUBMB Enzyme Nomenclature7.6.2.4
IntEnz7.6.2.4
MEDLINEFind literature relating to 7.6.2.4
MetaCyc7.6.2.4
UniProtKB/Swiss-Prot
Q94FB9, AB1D_ARATH;  F1RBC8, ABCD1_DANRE;  P33897, ABCD1_HUMAN;  
P48410, ABCD1_MOUSE;  D3ZHR2, ABCD1_RAT;  Q7JUN3, ABCD_DROME;  

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