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ENZYME entry: EC 7.6.2.6

Accepted Name
ABC-type guanine transporter.
Alternative Name(s)
guanine-transporting ATPase.
Reaction catalysed
ATP + guanine(out) + H2O <=> ADP + guanine(in) + H(+) + phosphate
Comment(s)
  • An ATP-binding cassette (ABC) type transporter found in insects that transports guanine and other purines into pigment granules in the eye, where they are converted to pteridine pigments.
  • The transporter is a hererodimer composed of two different peptides, each containing one membrane-spanning and one cytoplasmic ATP-binding domain.
  • In Drosophila, this transporter is encoded by the white and brown genes.
  • Formerly EC 3.6.3.37.
Cross-references
BRENDA7.6.2.6
EC2PDB7.6.2.6
ExplorEnz7.6.2.6
PRIAM enzyme-specific profiles7.6.2.6
KEGG Ligand Database for Enzyme Nomenclature7.6.2.6
IUBMB Enzyme Nomenclature7.6.2.6
IntEnz7.6.2.6
MEDLINEFind literature relating to 7.6.2.6
MetaCyc7.6.2.6
Rhea expert-curated reactions7.6.2.6
UniProtKB/Swiss-Prot
P12428, BROWN_DROME;  Q24739, BROWN_DROVI;  P10090, WHITE_DROME;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.6.2.-
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