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ENZYME

ENZYME entry: EC 7.6.2.8

PURL: https://purl.expasy.org/enzyme/EC/7.6.2.8
Accepted Name
ABC-type vitamin B12 transporter
Alternative Name(s)
vitamin B12 ABC transporter
vitamin B12-transporting ATPase
Reaction catalysed
an R-cob(III)alamin(out) + ATP + H2O = an R-cob(III)alamin(in) + ADP + phosphate + H(+)
Comment(s)
  • An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • Does not undergo phosphorylation during the transport process.
  • A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of cobalamin derivatives.
  • Formerly EC 3.6.3.33.
Cross-references
BRENDA7.6.2.8
EC2PDB7.6.2.8
ExplorEnz7.6.2.8
KEGG Ligand Database for Enzyme Nomenclature7.6.2.8
IUBMB Enzyme Nomenclature7.6.2.8
MEDLINEFind literature relating to 7.6.2.8
MetaCyc7.6.2.8
Rhea expert-curated reactions7.6.2.8
UniProtKB/Swiss-Prot
O14678, ABCD4_HUMANO89016, ABCD4_MOUSEB0R5G4, BTUDA_HALS3
Q9HQ18, BTUDA_HALSAA8AHA1, BTUD_CITK8A7ZMH7, BTUD_ECO24
B7US48, BTUD_ECO27B7MAS0, BTUD_ECO45B7L6I2, BTUD_ECO55
Q8X5W0, BTUD_ECO57B5YPZ7, BTUD_ECO5EB7NTS2, BTUD_ECO7I
B7MV91, BTUD_ECO81B7M1B8, BTUD_ECO8AC4ZYH1, BTUD_ECOBW
B1XG16, BTUD_ECODHA8A0Q1, BTUD_ECOHSA1ABP5, BTUD_ECOK1
Q0THB9, BTUD_ECOL5Q8FH28, BTUD_ECOL6B1IPL8, BTUD_ECOLC
P06611, BTUD_ECOLIB7N547, BTUD_ECOLUB6I8R4, BTUD_ECOSE
B1LE21, BTUD_ECOSMQ1RB86, BTUD_ECOUTQ6D654, BTUD_PECAS
Q7N3Q4, BTUD_PHOLLQ6LQ77, BTUD_PHOPRQ57PU4, BTUD_SALCH
B5FJ99, BTUD_SALDCB5QVV9, BTUD_SALEPB4TGI0, BTUD_SALHS
Q5PH81, BTUD_SALPAB5BA33, BTUD_SALPKP63352, BTUD_SALTI
P63351, BTUD_SALTYB2U358, BTUD_SHIB3Q321G6, BTUD_SHIBS
Q32FJ0, BTUD_SHIDSQ0T4R9, BTUD_SHIF8Q7C1M3, BTUD_SHIFL
Q3Z257, BTUD_SHISSB7VPD0, BTUD_VIBA3A7MVV6, BTUD_VIBC1
A5F1V0, BTUD_VIBC3Q9KSL1, BTUD_VIBCHC3LLU1, BTUD_VIBCM
Q87Q38, BTUD_VIBPAQ8D928, BTUD_VIBVUQ7MLE6, BTUD_VIBVY
A1JPQ1, BTUD_YERE8Q8ZDX6, BTUD_YERPEQ66A01, BTUD_YERPS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.6.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-