ENZYME entry: EC 1.1.1.141
| Accepted Name |
|---|
| 15-hydroxyprostaglandin dehydrogenase (NAD(+)).
|
| Alternative Name(s) |
|---|
| 15-hydroxyprostaglandin dehydrogenase. |
| Reaction catalysed |
|---|
| (5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD(+) <=> (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH |
| Comment(s) |
|---|
| Acts on prostaglandins E(2), F(2-alpha) and B(1), but not on
prostaglandin D(2) (cf. EC 1.1.1.196 and EC 1.1.1.197).
|
| Cross-references |
|---|
| PROSITE | PDOC00060 |
| BRENDA | 1.1.1.141 |
| EC2PDB | 1.1.1.141 |
| ExplorEnz | 1.1.1.141 |
| PRIAM enzyme-specific profiles | 1.1.1.141 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.141 |
| IUBMB Enzyme Nomenclature | 1.1.1.141 |
| IntEnz | 1.1.1.141 |
| MEDLINE | Find literature relating to 1.1.1.141 |
| MetaCyc | 1.1.1.141 |
| UniProtKB/Swiss-Prot |
|
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