ENZYME entry: EC 1.1.1.283

Accepted Name
Methylglyoxal reductase (NADPH-dependent).
Alternative Name(s)
Lactaldehyde dehydrogenase (NADP(+)).
Reaction catalysed
Lactaldehyde + NADP(+) <=> methylglyoxal + NADPH
Comment(s)
  • The enzyme from the yeast Saccharomyces cerevisiae catalyzes the conversion of methylglyoxal into lactaldehyde; the reverse reaction has not been demonstrated.
  • It differs in coenzyme requirement from EC 1.1.1.78, which is found in mammals.
  • It also acts on phenylglyoxal and glyoxal.
Cross-references
BRENDA1.1.1.283
EC2PDB1.1.1.283
ExplorEnz1.1.1.283
PRIAM enzyme-specific profiles1.1.1.283
KEGG Ligand Database for Enzyme Nomenclature1.1.1.283
IUBMB Enzyme Nomenclature1.1.1.283
IntEnz1.1.1.283
MEDLINEFind literature relating to 1.1.1.283
MetaCyc1.1.1.283
UniProtKB/Swiss-Prot
Q12068, GRE2_YEAST;  P83775, GRP2_CANAL;  O32210, GR_BACSU;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-