ENZYME entry: EC 1.1.1.329

Accepted Name
2-deoxy-scyllo-inosamine dehydrogenase.
Reaction catalysed
2-deoxy-scyllo-inosamine + NAD(P)(+) <=> 3-amino-2,3-dideoxy-scyllo-inosose + NAD(P)H
Cofactor(s)
Zn(2+).
Comment(s)
  • Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, neomycin and ribostamycin.
  • Cf. EC 1.1.99.38.
Cross-references
BRENDA1.1.1.329
EC2PDB1.1.1.329
ExplorEnz1.1.1.329
PRIAM enzyme-specific profiles1.1.1.329
KEGG Ligand Database for Enzyme Nomenclature1.1.1.329
IUBMB Enzyme Nomenclature1.1.1.329
IntEnz1.1.1.329
MEDLINEFind literature relating to 1.1.1.329
MetaCyc1.1.1.329
UniProtKB/Swiss-Prot
Q70KF0, DOIAD_MICEC;  Q53U21, DOIAD_STRFR;  Q6L743, DOIAD_STRKN;  
Q2MF72, DOIAD_STRLV;  Q4R0W1, DOIAD_STRRI;  Q2MFP3, DOIAD_STRRY;  
Q2MF22, DOIAD_STRSD;  

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