ENZYME entry: EC 1.1.99.38

Accepted Name
2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent).
Reaction catalysed
2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine <=> 3-amino-2,3-dideoxy-scyllo-inosose + 5'-deoxyadenosine + L-methionine
Cofactor(s)
Iron-sulfur.
Comment(s)
  • Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family.
  • The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme.
  • Cf. EC 1.1.1.329.
Cross-references
BRENDA1.1.99.38
EC2PDB1.1.99.38
ExplorEnz1.1.99.38
PRIAM enzyme-specific profiles1.1.99.38
KEGG Ligand Database for Enzyme Nomenclature1.1.99.38
IUBMB Enzyme Nomenclature1.1.99.38
IntEnz1.1.99.38
MEDLINEFind literature relating to 1.1.99.38
MetaCyc1.1.99.38
UniProtKB/Swiss-Prot
Q8G907, BTRN_BACCI

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