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ENZYME entry: EC 18.104.22.1684
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|Ecgonine methyl ester + NADP(+) <=> ecgonone methyl ester + NADPH|
- The enzyme from the plant Erythroxylum coca catalyzes the penultimate
step in the biosynthesis of cocaine.
- In vivo the reaction proceeds in the opposite direction.
- With NADH instead of NADPH the reaction rate is reduced to 14%.
- The enzyme also reduces tropinone, nortropinone and
6-hydroxytropinone but with lower reaction rates.
|PRIAM enzyme-specific profiles||22.214.171.1244|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.1994|
|IUBMB Enzyme Nomenclature||188.8.131.524|
|MEDLINE||Find literature relating to 184.108.40.2064|
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