Due to maintenance work, this service will not be available on Monday December 12th between 07.00 am and 9.00 am CEST.

ENZYME entry: EC 1.11.1.12

Accepted Name
Phospholipid-hydroperoxide glutathione peroxidase.
Alternative Name(s)
Peroxidation-inhibiting protein.
Reaction catalysed
2 glutathione + a hydroperoxy-fatty-acyl-[lipid] <=> glutathione disulfide + a hydroxy-fatty-acyl-[lipid] + H(2)O
Cofactor(s)
Se(2+).
Comment(s)
The products of action of EC 1.13.11.12 on phospholipids can act as acceptor; H(2)O(2) can also act, but much more slowly (cf. EC 1.11.1.9).
Cross-references
PROSITEPDOC00396
BRENDA1.11.1.12
EC2PDB1.11.1.12
ExplorEnz1.11.1.12
PRIAM enzyme-specific profiles1.11.1.12
KEGG Ligand Database for Enzyme Nomenclature1.11.1.12
IUBMB Enzyme Nomenclature1.11.1.12
IntEnz1.11.1.12
MEDLINEFind literature relating to 1.11.1.12
MetaCyc1.11.1.12
UniProtKB/Swiss-Prot
P52032, GPX1_ARATH;  O24296, GPX1_PEA;  O70325, GPX41_MOUSE;  
P36970, GPX41_RAT;  Q91XR9, GPX42_MOUSE;  Q91XR8, GPX42_RAT;  
Q9N2J2, GPX4_BOVIN;  Q32QL6, GPX4_CALJA;  Q06652, GPX4_CITSI;  
O49069, GPX4_GOSHI;  O23968, GPX4_HELAN;  P36969, GPX4_HUMAN;  
Q4AEH1, GPX4_HYLLA;  Q4AEH0, GPX4_MACFU;  Q9LEF0, GPX4_MESCR;  
P30708, GPX4_NICSY;  P36968, GPX4_PIG;  Q4AEH2, GPX4_PONPY;  
Q4AEG9, GPX4_SAPAP;  O24031, GPX4_SOLLC;  O23814, GPX4_SPIOL;  
Q9FXS3, GPX4_TOBAC;  O48646, GPX6_ARATH;  Q8SSH7, GPX_ENCCU;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.11.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.11.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-