ENZYME entry: EC 1.11.1.9

Accepted Name
Glutathione peroxidase.
Reaction catalysed
2 glutathione + H(2)O(2) <=> glutathione disulfide + 2 H(2)O
Cofactor(s)
Se(2+).
Comment(s)
Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
Cross-references
PROSITEPDOC00396
BRENDA1.11.1.9
EC2PDB1.11.1.9
ExplorEnz1.11.1.9
PRIAM enzyme-specific profiles1.11.1.9
KEGG Ligand Database for Enzyme Nomenclature1.11.1.9
IUBMB Enzyme Nomenclature1.11.1.9
IntEnz1.11.1.9
MEDLINEFind literature relating to 1.11.1.9
MetaCyc1.11.1.9
UniProtKB/Swiss-Prot
P06610, BTUE_ECOLI;  Q9CFV1, GPO_LACLA;  O32770, GPO_LACLM;  
O08368, GPWA_PSEWI;  P00435, GPX1_BOVIN;  O02621, GPX1_CAEEL;  
Q0EF99, GPX1_CALJA;  P83564, GPX1_CHLRE;  O23970, GPX1_HELAN;  
P07203, GPX1_HUMAN;  Q4AEI2, GPX1_HYLLA;  Q865R2, GPX1_MACFU;  
P11352, GPX1_MOUSE;  Q0EFA0, GPX1_PANTR;  Q8MJ14, GPX1_PIG;  
Q4AEI3, GPX1_PONPY;  P11909, GPX1_RABIT;  P04041, GPX1_RAT;  
Q4AEI1, GPX1_SAPAP;  Q00277, GPX1_SCHMA;  O59858, GPX1_SCHPO;  
P36014, GPX1_YEAST;  O04922, GPX2_ARATH;  O62327, GPX2_CAEEL;  
Q0EF98, GPX2_CALJA;  P18283, GPX2_HUMAN;  Q4AEH9, GPX2_HYLLA;  
Q4AEH8, GPX2_MACFU;  Q9JHC0, GPX2_MOUSE;  Q4AEI0, GPX2_PONPY;  
P83645, GPX2_RAT;  Q4AEH7, GPX2_SAPAP;  P38143, GPX2_YEAST;  
O22850, GPX3_ARATH;  P37141, GPX3_BOVIN;  Q95003, GPX3_CAEEL;  
P22352, GPX3_HUMAN;  Q4AEH5, GPX3_HYLLA;  Q4AEH4, GPX3_MACFU;  
P46412, GPX3_MOUSE;  Q5RFG3, GPX3_PONPY;  P23764, GPX3_RAT;  
Q4AEH3, GPX3_SAPAP;  Q8L910, GPX4_ARATH;  P81087, GPX4_PINPS;  
Q9LYB4, GPX5_ARATH;  O46607, GPX5_CANLF;  O75715, GPX5_HUMAN;  
P28714, GPX5_MACFA;  P21765, GPX5_MOUSE;  O18994, GPX5_PIG;  
P30710, GPX5_RAT;  P59796, GPX6_HUMAN;  Q91WR8, GPX6_MOUSE;  
Q64625, GPX6_RAT;  Q9SZ54, GPX7_ARATH;  A6QLY2, GPX7_BOVIN;  
Q96SL4, GPX7_HUMAN;  Q99LJ6, GPX7_MOUSE;  Q6IRC8, GPX8A_XENLA;  
Q5U583, GPX8B_XENLA;  Q8LBU2, GPX8_ARATH;  Q2NL01, GPX8_BOVIN;  
Q7ZV14, GPX8_DANRE;  Q8TED1, GPX8_HUMAN;  Q9D7B7, GPX8_MOUSE;  
Q4RSM6, GPX8_TETNG;  P67877, GPXC_BRUMA;  P67878, GPXC_BRUPA;  
P52033, GPXC_DIRIM;  P35666, GPXC_WUCBA;  Q98234, GPX_MCV1;  
G9JJU2, GPX_PROCL;  O77834, PRDX6_BOVIN;  P30041, PRDX6_HUMAN;  
Q2PFL9, PRDX6_MACFA;  P86215, PRDX6_MESAU;  O08709, PRDX6_MOUSE;  
Q9TSX9, PRDX6_PIG;  Q5R7E0, PRDX6_PONAB;  O35244, PRDX6_RAT;  
P23202, URE2_YEAST;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.11.1.-
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