ENZYME entry: EC 1.11.1.9

Accepted Name
Glutathione peroxidase.
Reaction catalysed
2 glutathione + H(2)O(2) <=> glutathione disulfide + 2 H(2)O
Cofactor(s)
Se(2+).
Comment(s)
Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
Cross-references
PROSITEPDOC00396
BRENDA1.11.1.9
EC2PDB1.11.1.9
ExplorEnz1.11.1.9
PRIAM enzyme-specific profiles1.11.1.9
KEGG Ligand Database for Enzyme Nomenclature1.11.1.9
IUBMB Enzyme Nomenclature1.11.1.9
IntEnz1.11.1.9
MEDLINEFind literature relating to 1.11.1.9
MetaCyc1.11.1.9
UniProtKB/Swiss-Prot
Q9CFV1, GPO_LACLA;  O32770, GPO_LACLM;  O08368, GPWA_PSEWI;  
P00435, GPX1_BOVIN;  O02621, GPX1_CAEEL;  Q0EF99, GPX1_CALJA;  
Q4AEI1, GPX1_CEBAP;  P83564, GPX1_CHLRE;  O23970, GPX1_HELAN;  
P07203, GPX1_HUMAN;  Q4AEI2, GPX1_HYLLA;  Q865R2, GPX1_MACFU;  
P11352, GPX1_MOUSE;  Q0EFA0, GPX1_PANTR;  Q8MJ14, GPX1_PIG;  
Q4AEI3, GPX1_PONPY;  P11909, GPX1_RABIT;  P04041, GPX1_RAT;  
Q00277, GPX1_SCHMA;  O59858, GPX1_SCHPO;  P36014, GPX1_YEAST;  
O04922, GPX2_ARATH;  O62327, GPX2_CAEEL;  Q0EF98, GPX2_CALJA;  
Q4AEH7, GPX2_CEBAP;  P18283, GPX2_HUMAN;  Q4AEH9, GPX2_HYLLA;  
Q4AEH8, GPX2_MACFU;  Q9JHC0, GPX2_MOUSE;  Q4AEI0, GPX2_PONPY;  
P83645, GPX2_RAT;  P38143, GPX2_YEAST;  O22850, GPX3_ARATH;  
P37141, GPX3_BOVIN;  Q95003, GPX3_CAEEL;  Q4AEH3, GPX3_CEBAP;  
P22352, GPX3_HUMAN;  Q4AEH5, GPX3_HYLLA;  Q4AEH4, GPX3_MACFU;  
P46412, GPX3_MOUSE;  Q5RFG3, GPX3_PONPY;  P23764, GPX3_RAT;  
Q8L910, GPX4_ARATH;  P81087, GPX4_PINPS;  Q9LYB4, GPX5_ARATH;  
O46607, GPX5_CANFA;  O75715, GPX5_HUMAN;  P28714, GPX5_MACFA;  
P21765, GPX5_MOUSE;  O18994, GPX5_PIG;  P30710, GPX5_RAT;  
P59796, GPX6_HUMAN;  Q91WR8, GPX6_MOUSE;  Q64625, GPX6_RAT;  
Q9SZ54, GPX7_ARATH;  A6QLY2, GPX7_BOVIN;  Q96SL4, GPX7_HUMAN;  
Q99LJ6, GPX7_MOUSE;  Q6IRC8, GPX8A_XENLA;  Q5U583, GPX8B_XENLA;  
Q8LBU2, GPX8_ARATH;  Q2NL01, GPX8_BOVIN;  Q7ZV14, GPX8_DANRE;  
Q8TED1, GPX8_HUMAN;  Q9D7B7, GPX8_MOUSE;  Q4RSM6, GPX8_TETNG;  
P67877, GPXC_BRUMA;  P67878, GPXC_BRUPA;  P52033, GPXC_DIRIM;  
P35666, GPXC_WUCBA;  Q98234, GPX_MCV1;  G9JJU2, GPX_PROCL;  
O77834, PRDX6_BOVIN;  P30041, PRDX6_HUMAN;  Q2PFL9, PRDX6_MACFA;  
P86215, PRDX6_MESAU;  O08709, PRDX6_MOUSE;  Q9TSX9, PRDX6_PIG;  
Q5R7E0, PRDX6_PONAB;  O35244, PRDX6_RAT;  P23202, URE2_YEAST;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.11.1.-
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